Efficacy and Safety of Gefitinib Plus Anlotinib for Patients with EGFR Positive Advanced Non-Small-Cell Lung Cancer: A Retrospective Exploratory Study

WX Hu, JC Peng, Y Wang, H Jin… - International Journal of …, 2022 - Taylor & Francis
… Totally, adverse events regardless … study was designed as a retrospective analysis and
some bias could not be avoided, and the patient management was not sufficient when compared

[HTML][HTML] … nervous system efficacy among gefitinib, erlotinib and afatinib in patients with epidermal growth factor receptor mutation-positive non-small cell lung cancer

HA Jung, SY Woo, SH Lee, JS Ahn… - … Lung Cancer …, 2020 - ncbi.nlm.nih.gov
… of CNS failure compared with gefitinib or erlotinib. However, our study, as a retrospective
study, has significant limitation for the accurate comparison of CNS efficacy, so cautious …

Comparing the effectiveness of different EGFR‐TKIs in patients with EGFR mutant nonsmallcell lung cancer: a retrospective cohort study in Taiwan

YY Hsieh, WT Fang, YW Lo, YH Chen… - … journal of cancer, 2020 - Wiley Online Library
effectiveness compared to gefitinib after performing a multivariate Cox regression analysis.
… with better ECOG PS to avoid higher grade (grade ¾) adverse events after afatinib treatment…

[HTML][HTML] … erlotinib for treatment-naïve elderly patients with epidermal growth factor receptor-mutated advanced non-small-cell lung cancer: a multi-institute retrospective …

LJ Hung, PC Hsu, CT Yang, CHS Kuo… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
… /interruption), drug discontinuation, tumor response, adverse events (AEs), and subsequent
… for older patients compared to erlotinib or gefitinib. The characteristics of younger and older …

[HTML][HTML] Comparison of first-generation EGFR-TKIs (gefitinib, erlotinib, and icotinib) as adjuvant therapy in resected NSCLC patients with sensitive EGFR mutations

Q He, J Liu, X Cai, M He, C Li, H Liang… - … Lung Cancer …, 2021 - ncbi.nlm.nih.gov
… proportion of early stage non-small cell lung cancer (NSCLC) … a retrospective study to compare
the clinical efficacy among … had a similar detrimental effect in patients with stage IA stage …

[HTML][HTML] Efficacy and tolerability of erlotinib 100 mg/d vs. gefitinib 250 mg/d in EGFR-mutated advanced non-small cell lung cancer (E100VG250): an open-label …

S Zhao, Z Zhang, W Fang, Y Zhang, Z Zhang… - Frontiers in …, 2020 - frontiersin.org
Retrospective studies also supported this notion … difference was observed in the incidence
of adverse events of any grade or adverse events of grade 3–4 between erlotinib and gefitinib. …

[HTML][HTML] Efficacy and safety of erlotinib combined with bevacizumab in the treatment of non-small cell lung cancer: a systematic review and meta-analysis

K Zhou, S Zhao, W Guo, L Ding - Medicine, 2020 - journals.lww.com
… We compared the effects of erlotinib+bevacizumab … and severity of adverse events. We
also conducted subgroup … explore the efficacy and adverse events of erlotinib+bevacizumab …

Survival benefits from afatinib compared with gefitinib and erlotinib among patients with common EGFR mutation in first‐line setting

WC Kwok, JCM Ho, TCC Tam, MSM Ip… - … Cancer, 2022 - Wiley Online Library
… advanced and metastatic non-small cell lung cancer (NSCLC) … adverse effects and grade
3 gastrointestinal adverse effectsefficacy, compared to other first-generation EGFR-TKIs, for …

… third-generation epidermal growth factor receptor tyrosine kinase inhibitors as first-line treatment in patients with non-small-cell lung cancer: a retrospective analysis

S Mitsuya, K Tsuruoka, K Kanaoka… - Anticancer …, 2021 - ar.iiarjournals.org
… a comparative study of first-generation EGFR-TKIs gefitinib and … Herein, we retrospectively
evaluated the efficacy and safety of … All patients reported at least one adverse event (Table III). …

[HTML][HTML] … and effectiveness of afatinib for poor performance status patients with EGFR-mutation-positive non-small-cell lung cancer: a retrospective cohort study

CE Wu, CF Chang, CY Huang, CT Yang, CHS Kuo… - BMC cancer, 2021 - Springer
… This study aimed to retrospectively review the clinical … Data on adverse events were
collected to evaluate general … 2015, compared the efficacy of three different TKIs—gefitinib, …